The Mercure Hotel & Residenz Frankfurt Messe is located a short distance from both the convention center and the exhibition center. Also nearby one will find one of Frankfurt's busiest streets for shopping which is just over 2 miles away and can be accessed via a nearby train station. From the Mercure Hotel & Residenz Frankfurt Messe it is an approximately 20 minute ride to the Frankfurt airport.

There are 424 rooms in total at the Mercure Hotel & Residenz Frankfurt Messe. Each of these rooms counts among its standard amenities air-conditioning, direct-dial telephone service, Internet access via a wireless LAN, and a minibar. Every room is provided with a balcony.

The Mercure Hotel & Residenz Frankfurt Messe is stocked with modern amenities suitable for those traveling for business or pleasure purposes. Among its amenities are a spa, a Jacuzzi and a gym provided with workout equipment. There is also a business center on-site which can accommodate meetings with up to 100 attendees. A restaurant with terrace dining rounds out the amenities.